On tirzepatide, Fridays' no-membership structure does more work than it does on semaglutide, because the competitors charging memberships are charging them on top of higher medication prices.
Compounded tirzepatide is advertised from $198 a month, with the membership included at $0. Against the all-in figures — Eden at roughly $298, Measured at roughly $268, Mochi at $169, CoreAge Rx at $129 — Fridays sits mid-pack while bundling considerably more support than any of them.
It also offers an oral tirzepatide route alongside the injection, which few competitors publish, and branded Zepbound at $1,828 a month for anyone escalating to the FDA-approved product.
The same caveat applies
The pricing page displayed $198 and $240 for compounded tirzepatide at the same time, with $389 quoted on an annual plan, alongside unrendered "Save up to $xxx" placeholders. The $198 depends on a promo code and a seasonal promotion the company reserves the right to withdraw at any time.
Its comparison chart also rates unnamed competitors at $149 a month for membership fees without identifying them, which is not a comparison a reader can check.
What it actually costs per year
Advertised prices in this category are usually medication only. Add the membership back in and the ranking changes. Pick a provider, or enter the quote you were given.
One-month semaglutide rate. Starting at $79/month equivalent requires a 12-month plan ($948 total); confirm payment and renewal terms.
- First month
- $139
- Every month after
- $139
- Total over 12 months
- $1,668
No membership on this plan, so every dollar goes to medication and care.
Figures are the providers' own published prices as of our last review of each. Promotional rates, multi-month prepayment and dose changes can all move these numbers — confirm at checkout.
What compounded tirzepatide actually is
Tirzepatide is the active ingredient in Mounjaro and Zepbound, both FDA-approved products from Eli Lilly. Unlike semaglutide, it acts on two receptors — GLP-1 and GIP — which is the basis for the larger average weight reductions seen in its trials. A compounded version is prepared by a pharmacy and is not FDA-approved or FDA-evaluated.
Compounded tirzepatide is consistently more expensive than compounded semaglutide, typically by $50 to $100 a month. That gap is real and reflects the raw material, so a provider pricing them identically is worth a question rather than a celebration.
Dosing usually starts at 2.5 mg weekly and escalates in 2.5 mg steps. As with semaglutide, dose-flat pricing is worth substantially more than a low starting price, because the starting dose is not the dose most people end up on.
Side effects mirror semaglutide's — predominantly gastrointestinal, worst after dose increases — though some patients report tirzepatide is better tolerated at equivalent efficacy. That is an individual matter and not something a telehealth intake form can predict for you.
Before you buy from anyone
- Get the total monthly cost in writing — medication plus any membership, not the headline figure.
- Ask whether the price changes as your dose increases. This is where most of the money is lost.
- Ask which pharmacy compounds it, and whether it is a 503A or 503B facility.
- Confirm what happens if you stop after one month, and whether there is an auto-rebill.
- Ask whether a refund is available if a provider declines to prescribe.
- Tell the prescriber every medication and supplement you take, including anything bought online.