Measured's tirzepatide is priced like a premium product, and unusually for this category, there is an identifiable premium service attached to it.
Compounded tirzepatide is $219 a month with medication included, plus a membership from $49 — about $268 all-in. That is the highest compounded tirzepatide medication price we verified, ahead of Eden's $199 and well ahead of CoreAge Rx's $129.
The case for paying it rests entirely on the care model. Obesity-trained providers, registered dietitians and care coordinators, all reachable by unlimited messaging, is a materially different offer from a questionnaire and a shipped vial. For tirzepatide specifically — the more potent molecule, with a more demanding titration — having a clinician who will actually answer questions has practical value.
Where the dietitian access pays off
Lean mass loss is the most consequential downside of rapid weight loss, and tirzepatide produces the fastest weight loss in this drug class. Dietitian access aimed at protein intake and resistance training addresses the main risk of the drug you are taking, which is a more defensible use of a membership fee than most of what this industry bundles.
Your muscle-protection numbers
Weight lost on a GLP-1 is not all fat. Protein intake and resistance training are the two levers with the best evidence behind them. Set your weight to see the targets.
Daily protein target
120–200 g
Roughly 30 g at each of four eating occasions gets you to the bottom of that range.
Resistance training
2–3 ×/week
Full-body sessions covering legs, push and pull. Loaded movement is the signal that tells your body to keep the muscle.
General nutrition and activity information, not medical advice. Protein targets can be inappropriate in kidney disease and some other conditions — check with your clinician before changing your intake.
What is missing
No branded medication price is published. No BMI criteria, exclusions or refund policy are published. Pharmacies are not named. And the longevity add-ons — NAD+ at $159, sermorelin at $149, glutathione, oxytocin nasal spray — sit in the same grid as the GLP-1 lines, which blurs the line between what is clinically indicated and what is being sold.
What it actually costs per year
Advertised prices in this category are usually medication only. Add the membership back in and the ranking changes. Pick a provider, or enter the quote you were given.
One-month semaglutide rate. Starting at $79/month equivalent requires a 12-month plan ($948 total); confirm payment and renewal terms.
- First month
- $139
- Every month after
- $139
- Total over 12 months
- $1,668
No membership on this plan, so every dollar goes to medication and care.
Figures are the providers' own published prices as of our last review of each. Promotional rates, multi-month prepayment and dose changes can all move these numbers — confirm at checkout.
What compounded tirzepatide actually is
Tirzepatide is the active ingredient in Mounjaro and Zepbound, both FDA-approved products from Eli Lilly. Unlike semaglutide, it acts on two receptors — GLP-1 and GIP — which is the basis for the larger average weight reductions seen in its trials. A compounded version is prepared by a pharmacy and is not FDA-approved or FDA-evaluated.
Compounded tirzepatide is consistently more expensive than compounded semaglutide, typically by $50 to $100 a month. That gap is real and reflects the raw material, so a provider pricing them identically is worth a question rather than a celebration.
Dosing usually starts at 2.5 mg weekly and escalates in 2.5 mg steps. As with semaglutide, dose-flat pricing is worth substantially more than a low starting price, because the starting dose is not the dose most people end up on.
Side effects mirror semaglutide's — predominantly gastrointestinal, worst after dose increases — though some patients report tirzepatide is better tolerated at equivalent efficacy. That is an individual matter and not something a telehealth intake form can predict for you.
Before you buy from anyone
- Get the total monthly cost in writing — medication plus any membership, not the headline figure.
- Ask whether the price changes as your dose increases. This is where most of the money is lost.
- Ask which pharmacy compounds it, and whether it is a 503A or 503B facility.
- Confirm what happens if you stop after one month, and whether there is an auto-rebill.
- Ask whether a refund is available if a provider declines to prescribe.
- Tell the prescriber every medication and supplement you take, including anything bought online.
