Noom prices compounded tirzepatide and semaglutide identically at $179, which is unusual, and offers both inside the same microdose programme.
Against the all-in field — CoreAge Rx at $129, Mochi at $169, Fridays at $198, Measured at $268, Eden at $298 — $179 is competitive. The question is not price but dose.
Tirzepatide's trial results, the largest in this drug class, came from standard titration in 2.5 mg steps toward maintenance doses. A microdose programme is a different intervention. If your goal is the weight loss you have read about, you should establish explicitly what doses this programme will take you to.
If your goal is sustained behaviour change with a pharmacological assist — and for many people that is the more durable goal — Noom's coaching infrastructure is the best-developed in this set, and a lower dose taken consistently within a structured programme is a defensible plan.
Your muscle-protection numbers
Weight lost on a GLP-1 is not all fat. Protein intake and resistance training are the two levers with the best evidence behind them. Set your weight to see the targets.
Daily protein target
120–200 g
Roughly 30 g at each of four eating occasions gets you to the bottom of that range.
Resistance training
2–3 ×/week
Full-body sessions covering legs, push and pull. Loaded movement is the signal that tells your body to keep the muscle.
General nutrition and activity information, not medical advice. Protein targets can be inappropriate in kidney disease and some other conditions — check with your clinician before changing your intake.
What compounded tirzepatide actually is
Tirzepatide is the active ingredient in Mounjaro and Zepbound, both FDA-approved products from Eli Lilly. Unlike semaglutide, it acts on two receptors — GLP-1 and GIP — which is the basis for the larger average weight reductions seen in its trials. A compounded version is prepared by a pharmacy and is not FDA-approved or FDA-evaluated.
Compounded tirzepatide is consistently more expensive than compounded semaglutide, typically by $50 to $100 a month. That gap is real and reflects the raw material, so a provider pricing them identically is worth a question rather than a celebration.
Dosing usually starts at 2.5 mg weekly and escalates in 2.5 mg steps. As with semaglutide, dose-flat pricing is worth substantially more than a low starting price, because the starting dose is not the dose most people end up on.
Side effects mirror semaglutide's — predominantly gastrointestinal, worst after dose increases — though some patients report tirzepatide is better tolerated at equivalent efficacy. That is an individual matter and not something a telehealth intake form can predict for you.
Before you buy from anyone
- Get the total monthly cost in writing — medication plus any membership, not the headline figure.
- Ask whether the price changes as your dose increases. This is where most of the money is lost.
- Ask which pharmacy compounds it, and whether it is a 503A or 503B facility.
- Confirm what happens if you stop after one month, and whether there is an auto-rebill.
- Ask whether a refund is available if a provider declines to prescribe.
- Tell the prescriber every medication and supplement you take, including anything bought online.