Midi publishes one floor price covering both its compounded GLP-1 and its GLP-1/GIP, which is worth pressing on, because almost nobody else prices the two molecules the same.
The published line is compounded GLP-1 and GLP-1/GIP starting at $164 per four-week supply, varying by medication, format and dose, with shipping and supplies included. Across the rest of the market, compounded tirzepatide costs meaningfully more than semaglutide — CoreAge Rx charges $79 on a 12-month plan and $129 on a 12-month plan, Eden $99 and $199, Measured $119 and $219.
So either Midi's dual agonist is unusually cheap, or the $164 floor applies mainly to semaglutide and tirzepatide sits higher within the stated range. The page does not resolve it, which makes this the first question to ask.
The microdose route
Midi advertises microdosing from $34 a week for eligible patients, prescribed where clinically appropriate — roughly $147 over four weeks, its cheapest published route into treatment.
Where a dose sits on the studied ladder
Move the slider to see whether a dose is one the weight-loss trials actually used. Doses below the studied range may still suit you — they simply have no trial result attached.
Standard titration step
Standard schedule: Weeks 1–4
The standard starting dose. Intended to build tolerance, not to produce weight loss.
In the trial programme behind Wegovy, adults reached a 2.4 mg weekly maintenance dose and lost an average of about 15% of body weight over 68 weeks.
Titration schedules are the standard ones for the approved products and are shown for orientation, not as a dosing instruction. Compounded products are not FDA-approved and your prescriber sets your schedule. Never change a dose on the basis of a web page.
What the visit structure buys
Fifteen-minute follow-ups exist specifically to adjust dose over time, which matches tirzepatide's stepwise titration well. A clinician reviewing you at each step is a better fit for this molecule than a chat inbox, and it is covered where Midi is in-network.
Self-pay, those same follow-ups are $150 each, so the cadence that makes the clinical model good also makes the cash model expensive. Price both before choosing.
What it actually costs per year
Advertised prices in this category are usually medication only. Add the membership back in and the ranking changes. Pick a provider, or enter the quote you were given.
One-month semaglutide rate. Starting at $79/month equivalent requires a 12-month plan ($948 total); confirm payment and renewal terms.
- First month
- $139
- Every month after
- $139
- Total over 12 months
- $1,668
No membership on this plan, so every dollar goes to medication and care.
Figures are the providers' own published prices as of our last review of each. Promotional rates, multi-month prepayment and dose changes can all move these numbers — confirm at checkout.
What compounded tirzepatide actually is
Tirzepatide is the active ingredient in Mounjaro and Zepbound, both FDA-approved products from Eli Lilly. Unlike semaglutide, it acts on two receptors — GLP-1 and GIP — which is the basis for the larger average weight reductions seen in its trials. A compounded version is prepared by a pharmacy and is not FDA-approved or FDA-evaluated.
Compounded tirzepatide is consistently more expensive than compounded semaglutide, typically by $50 to $100 a month. That gap is real and reflects the raw material, so a provider pricing them identically is worth a question rather than a celebration.
Dosing usually starts at 2.5 mg weekly and escalates in 2.5 mg steps. As with semaglutide, dose-flat pricing is worth substantially more than a low starting price, because the starting dose is not the dose most people end up on.
Side effects mirror semaglutide's — predominantly gastrointestinal, worst after dose increases — though some patients report tirzepatide is better tolerated at equivalent efficacy. That is an individual matter and not something a telehealth intake form can predict for you.
Before you buy from anyone
- Get the total monthly cost in writing — medication plus any membership, not the headline figure.
- Ask whether the price changes as your dose increases. This is where most of the money is lost.
- Ask which pharmacy compounds it, and whether it is a 503A or 503B facility.
- Confirm what happens if you stop after one month, and whether there is an auto-rebill.
- Ask whether a refund is available if a provider declines to prescribe.
- Tell the prescriber every medication and supplement you take, including anything bought online.