Tirzepatide is the molecule where prepayment discounts bite hardest, because the monthly rates are higher and the titration is longer.
Ondra publishes compounded tirzepatide at $219 a month billed monthly, $183 a month on three months at $549, $167 a month on six months at $999, or $142 a month on twelve months at $1,699. The same price applies across every dose within a plan.
Compounded tirzepatide: sustained monthly cost including any mandatory fee
| Provider | Sustained monthly | Commitment | Pharmacy named? |
|---|---|---|---|
| Ondra Health (12-month) | $142 | $1,699 upfront | Yes — Hallandale, Vials RX |
| CoreAge Rx | $129 monthly equivalent | 12-month plan ($1,548 total) | No |
| Ondra Health (6-month) | $167 | $999 upfront | Yes |
| Mochi Health | $169 | None | No |
| Fridays | $198 | Promo code required | No |
| Ondra Health (monthly) | $219 | None | Yes |
| Precision Telemed | $249.99 | None | Yes — Rush Pharmacy |
| Measured | $268 | None | No |
| Eden | $298 | None | No |
Scroll the table sideways to see every column.
Two things stand out from that table. First, prepayment is the only route to a rate below CoreAge Rx's flat $129. Second, the three providers naming their pharmacies — Ondra, Precision Telemed and OrderlyMeds — are not the cheapest, which is worth remembering when price is the only thing you are comparing.
What you are committing to
$1,699 upfront buys twelve months at a dose ladder running from 2.5 mg upward. If you stop at month four because you cannot tolerate it, Ondra publishes no refund policy that tells you what happens to the balance.
What it actually costs per year
Advertised prices in this category are usually medication only. Add the membership back in and the ranking changes. Pick a provider, or enter the quote you were given.
One-month semaglutide rate. Starting at $79/month equivalent requires a 12-month plan ($948 total); confirm payment and renewal terms.
- First month
- $139
- Every month after
- $139
- Total over 12 months
- $1,668
No membership on this plan, so every dollar goes to medication and care.
Figures are the providers' own published prices as of our last review of each. Promotional rates, multi-month prepayment and dose changes can all move these numbers — confirm at checkout.
What compounded tirzepatide actually is
Tirzepatide is the active ingredient in Mounjaro and Zepbound, both FDA-approved products from Eli Lilly. Unlike semaglutide, it acts on two receptors — GLP-1 and GIP — which is the basis for the larger average weight reductions seen in its trials. A compounded version is prepared by a pharmacy and is not FDA-approved or FDA-evaluated.
Compounded tirzepatide is consistently more expensive than compounded semaglutide, typically by $50 to $100 a month. That gap is real and reflects the raw material, so a provider pricing them identically is worth a question rather than a celebration.
Dosing usually starts at 2.5 mg weekly and escalates in 2.5 mg steps. As with semaglutide, dose-flat pricing is worth substantially more than a low starting price, because the starting dose is not the dose most people end up on.
Side effects mirror semaglutide's — predominantly gastrointestinal, worst after dose increases — though some patients report tirzepatide is better tolerated at equivalent efficacy. That is an individual matter and not something a telehealth intake form can predict for you.
Before you buy from anyone
- Get the total monthly cost in writing — medication plus any membership, not the headline figure.
- Ask whether the price changes as your dose increases. This is where most of the money is lost.
- Ask which pharmacy compounds it, and whether it is a 503A or 503B facility.
- Confirm what happens if you stop after one month, and whether there is an auto-rebill.
- Ask whether a refund is available if a provider declines to prescribe.
- Tell the prescriber every medication and supplement you take, including anything bought online.