Coby Health is the most useful provider in this market to study, because it documents in public the pricing model everyone else runs quietly.
Its published ladder: $239 a month at 2.5 mg, $299 at 5 mg, $329 at 7.5 mg, $379 at 10 mg, and $439 at 12.5 mg and 15 mg. Alongside it, Coby publishes the titration schedule those doses follow — month one at 2.5 mg, month two at 5 mg, and so on to month five and beyond at 12.5 mg.
Put the two together and the company has told you, on its own site, that a patient following its own schedule will be paying 84% more by month five than the advertised starting rate.
What it costs against a flat-rate provider
Precision Telemed charges $249.99 at every dose from 2 mg to 15 mg. Coby is $11 cheaper at the starting dose and $189 a month more expensive at 12.5 mg. Over a year following a standard titration, that difference compounds into well over a thousand dollars.
CoreAge Rx at $129 flat and Ondra Health at $142 on an annual plan are cheaper than Coby at every single rung of the ladder, including the promotional first one.
What it actually costs per year
Advertised prices in this category are usually medication only. Add the membership back in and the ranking changes. Pick a provider, or enter the quote you were given.
One-month semaglutide rate. Starting at $79/month equivalent requires a 12-month plan ($948 total); confirm payment and renewal terms.
- First month
- $139
- Every month after
- $139
- Total over 12 months
- $1,668
No membership on this plan, so every dollar goes to medication and care.
Figures are the providers' own published prices as of our last review of each. Promotional rates, multi-month prepayment and dose changes can all move these numbers — confirm at checkout.
The bundles, and what they cost you
Multi-month same-dose bundles are where Coby becomes competitive: $189 a month for three months at 2.5 mg, or $179 a month across six. Titration bundles are also offered, covering a planned climb — $309 a month for a 5 mg to 10 mg progression over three months, for instance.
The catch is structural. A same-dose bundle fixes the dose for the period you have bought. If your clinician concludes at week six that you should move up, you are choosing between the clinical recommendation and the money you have already spent. That is the wrong incentive to introduce into a titration.
Where a dose sits on the studied ladder
Move the slider to see whether a dose is one the weight-loss trials actually used. Doses below the studied range may still suit you — they simply have no trial result attached.
Standard titration step
Standard schedule: Weeks 1–4
The standard starting dose. Intended to build tolerance, not to produce weight loss.
In the trial programme behind Wegovy, adults reached a 2.4 mg weekly maintenance dose and lost an average of about 15% of body weight over 68 weeks.
Titration schedules are the standard ones for the approved products and are shown for orientation, not as a dosing instruction. Compounded products are not FDA-approved and your prescriber sets your schedule. Never change a dose on the basis of a web page.
What compounded tirzepatide actually is
Tirzepatide is the active ingredient in Mounjaro and Zepbound, both FDA-approved products from Eli Lilly. Unlike semaglutide, it acts on two receptors — GLP-1 and GIP — which is the basis for the larger average weight reductions seen in its trials. A compounded version is prepared by a pharmacy and is not FDA-approved or FDA-evaluated.
Compounded tirzepatide is consistently more expensive than compounded semaglutide, typically by $50 to $100 a month. That gap is real and reflects the raw material, so a provider pricing them identically is worth a question rather than a celebration.
Dosing usually starts at 2.5 mg weekly and escalates in 2.5 mg steps. As with semaglutide, dose-flat pricing is worth substantially more than a low starting price, because the starting dose is not the dose most people end up on.
Side effects mirror semaglutide's — predominantly gastrointestinal, worst after dose increases — though some patients report tirzepatide is better tolerated at equivalent efficacy. That is an individual matter and not something a telehealth intake form can predict for you.
Before you buy from anyone
- Get the total monthly cost in writing — medication plus any membership, not the headline figure.
- Ask whether the price changes as your dose increases. This is where most of the money is lost.
- Ask which pharmacy compounds it, and whether it is a 503A or 503B facility.
- Confirm what happens if you stop after one month, and whether there is an auto-rebill.
- Ask whether a refund is available if a provider declines to prescribe.
- Tell the prescriber every medication and supplement you take, including anything bought online.